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{{Tab On|Quickview|smpA}}{{Tab|Gene|smpA}}{{Tab|Gene Product(s)|smpA}}{{Tab|Expression|smpA}}{{Tab|Evolution|smpA}}{{Tab|On One Page|smpA}}{{TabsBottom}}
{{Tab On|Quickview|bamE}}{{Tab|Gene|bamE}}{{Tab|Gene Product(s)|bamE}}{{Tab|Expression|bamE}}{{Tab|Evolution|bamE}}{{Tab|On One Page|bamE}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[smpA:Gene|''smpA]]'' (synonyms: ''ECK2613, b2617, JW2598, smqA, bamE '')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoGene'/>
''bamE''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[smpA:Gene_Product(s)|SmpA product]]<ref name='LIB:Riley_2006'/>: small membrane lipoprotein product, B2617 product, SmqA product; BamE product <ref name='LIB:EcoGene'/>
''ECK2613, b2617, JW2598, smqA, bamE '', smpA<ref name='LIB:Riley_2006'/><ref name='LIB:EcoGene'/>, smpA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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SmpA small membrane protein A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
BamE small membrane protein A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:Outer Membrane Protein Assembly Complex|Outer Membrane Protein Assembly Complex]]<ref name='LIB:EcoCyc11.1'/>


Stabilizes BamABCD OM biogenesis complex; member of a BamABCDBamE multiprotein complex; probable lipoprotein, Cys conserved<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''small membrane lipoprotein<ref name='LIB:Riley_2006'/>, B2617<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SmqA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BamE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BamE <ref name='LIB:EcoGene'/> , ECK2613, JW2598, smpA, smqA, b2617''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:smpA|smpA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:bamE|bamE]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=smpA&s=search]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=smpA&loc=MG1655%3A2751627..2751968,W3110%3A2752261..2752602,DH10B%3A2843392..2843733,REL606%3A2675089..2675241,BW2952%3A2637439..2637780]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2637439&end=2637780&gene=smpA&aa=msdpfgtntwfyvfrqqpghegvtqqtltltfnssgvltnidnkpalsgn]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=smpA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=smpA]]&nbsp;&nbsp;
 
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The Bam complex in ''E. coli'' consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA).  Letters have been assigned on the basis of molecular weight, from highest to lowest <ref name='LIB:EcoGene'/>.
The Bam complex in ''E. coli'' consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA).  Letters have been assigned on the basis of molecular weight, from highest to lowest <ref name='LIB:EcoGene'/>.
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smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:46, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

bamE

Gene Synonym(s)

ECK2613, b2617, JW2598, smqA, bamE , smpA[1][2], smpA

Product Desc.

BamE small membrane protein A[3][4] Component of Outer Membrane Protein Assembly Complex[4]

Stabilizes BamABCD OM biogenesis complex; member of a BamABCDBamE multiprotein complex; probable lipoprotein, Cys conserved[2]

Product Synonyms(s)

small membrane lipoprotein[1], B2617[3][1], SmqA[3][1], BamE[3][1], BamE [2] , ECK2613, JW2598, smpA, smqA, b2617

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): bamE[3]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

A consensus has been reached for renaming the genes that encode components of the outer membrane β-barrel assembly machine, (formerly known as the YaeT complex of E. coli or the Omp85 complex of N. meningitidis). The new designation for this multi-component structure is the Bam complex (for beta-barrel assembly machine).

The Bam complex in E. coli consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA). Letters have been assigned on the basis of molecular weight, from highest to lowest [2].

[back to top]


smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.[2]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
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