malT:Quickview: Difference between revisions

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{|   id="J49aeebd5c808c"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[malT:Gene|''malT]]'' (synonyms: ''ECK3405, b3418, JW3381, malA'')<ref name='LIB:Riley_2006'/>
''malT''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[malT:Gene_Product(s)|MalT product, MalT product]]<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>: B3418 product, MalA product
''ECK3405, b3418, JW3381, malA''<ref name='LIB:Riley_2006'/>, malA''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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MalT transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
MalT transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


ATP-dependent transcriptional activator for the mal regulon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused conserved protein<ref name='LIB:Riley_2006'/>, DNA-binding transcriptional activator, maltotriose-ATP-binding<ref name='LIB:Riley_2006'/>, MalA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3418<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3405, JW3381, malA, b3418''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:malT|malT]]<ref name='LIB:EcoCyc10.6'/>, OP00128  
transcription unit(s): [[:Category:Txn_unit:malT|malT]]<ref name='LIB:EcoCyc10.6'/>, OP00128  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=malT&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10562]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000555&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=malT&loc=MG1655%3A3551107..3553812,W3110%3A4087331..4084626,REL606%3A3481685..3484390,DH10B%3A3648852..3651557,BW2952%3A3439601..3442306]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3439601&end=3442306&gene=malT&aa=mlipsklsrpvrldhtvvrerllaklsgannfrlalitspagygkttlisqwaagkndigwysldegdnqqerfasyliaavqqatnghcaicetmaqkrqyasltslfaqlfielaewhsplylviddyhlitnpvihesmrffirhqpenltlvvlsrnlpqlgianlrvrdqlleigsqqlafthqeakqffdcrlsspieaaessricddvsgwatalqlialsarqnthsahksarrlaginashlsdylvdevldnvdlatrhfllksailrsmndalitrvtgeengqmrleeierqglflqrmddtgewfcyhplfgnflrqrcqwelaaelpeihraaaeswmaqgfpseaihhalaagdalmlrdillnhawslfnhselslleeslkalpwdsllenpqlvllqawlmqsqhrygevntllaraeheikdiredtmhaefnalraqvaindgnpdeaerlaklaleelppgwfysrivatsvlgevlhckgeltrslalmqqteqmarqhdvwhyalwsliqqseilfaqgflqtawetqekafqlineqhleqlpmheflvriraqllwawarldeaeasarsgievlssyqpqqqlqclamliqcslargdldnarsqlnrlenllgngkyhsdwisnankvrviywqmtgdkaaaanwlrhtakpefannhflqgqwrniaraqillgefepaeivleelnenarslrlmsdlnrnllllnqlywqagrksdaqrvlldalklanrtgfishfviegeamaqqlrqliqlntlpeleqhraqrilreinqhhrhkfahfdenfverllnhpevpelirtspltqrewqvlgliysgysneqiagelevaattikthirnlyqklgvahrqdavqhaqqllkmmgygv]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=malT+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=malT]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Activated by maltotriose and ATP to form active oligomers. Signal transduction ATPases with numerous domains (STAND) protein. ATP hydrolysis is not required for transcription activation (Richet, 1989), but is required to recycle back to the inactive form, which has ADP, not ATP bound (Marquenet, 2007). MalY (Clausen, 2000; Schreiber, 2000), MalK (Reyes, 1988; Panagiotidis, 1998; Bohm, 2002) and Aes (Joly, 2002) negatively regulate MalT activity by binding and blocking maltotriose activation. MalT is required for phage lambda sensitivity.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

malT

Gene Synonym(s)

ECK3405, b3418, JW3381, malA[1], malA

Product Desc.

MalT transcriptional activator[2][3]

ATP-dependent transcriptional activator for the mal regulon[4]

Product Synonyms(s)

fused conserved protein[1], DNA-binding transcriptional activator, maltotriose-ATP-binding[1], MalA[2][1], B3418[2][1] , ECK3405, JW3381, malA, b3418

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): malT[2], OP00128

Regulation/Activity
Quick Links



        

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Notes

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Activated by maltotriose and ATP to form active oligomers. Signal transduction ATPases with numerous domains (STAND) protein. ATP hydrolysis is not required for transcription activation (Richet, 1989), but is required to recycle back to the inactive form, which has ADP, not ATP bound (Marquenet, 2007). MalY (Clausen, 2000; Schreiber, 2000), MalK (Reyes, 1988; Panagiotidis, 1998; Bohm, 2002) and Aes (Joly, 2002) negatively regulate MalT activity by binding and blocking maltotriose activation. MalT is required for phage lambda sensitivity.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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