macB:Quickview: Difference between revisions

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{|   id="W49aeebb584e65"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[macB:Gene|''macB]]'' (synonyms: ''ECK0870, b0879, JW0863, ybjZ'')<ref name='LIB:Riley_2006'/>
''macB''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[macB:Gene_Product(s)|MacB product]]<ref name='LIB:Riley_2006'/>: fused macrolide transporter subunits of ABC superfamily: ATP-binding component product, membrane component product, YbjZ product, B0879 product
''ECK0870, b0879, JW0863, ybjZ''<ref name='LIB:Riley_2006'/>, ybjZ''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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MacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
MacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:MacAB macrolide efflux transporter complex|MacAB macrolide efflux transporter complex]]<ref name='LIB:EcoCyc10.6'/>
Component of [[:Category:Complex:MacAB macrolide efflux transporter complex|MacAB macrolide efflux transporter complex]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:MacAB macrolide efflux transporter complex|MacAB-TolC Macrolide Efflux Transport System]]<ref name='LIB:EcoCyc11.1'/>


ABC-type macrolide efflux transporter, with MacA and TolC<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused macrolide transporter subunits of ABC superfamily: ATP-binding component<ref name='LIB:Riley_2006'/>, membrane component<ref name='LIB:Riley_2006'/>, YbjZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MacB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B0879<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0870, JW0863, ybjZ, b0879''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:macB|macB]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:macAB|macAB]]<ref name='LIB:EcoCyc11.1'/>  
transcription unit(s): [[:Category:Txn_unit:macB|macB]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:macAB|macAB]]<ref name='LIB:EcoCyc11.1'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=macB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G6462]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120003062&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=macB&loc=MG1655%3A919570..921516,W3110%3A920769..922715,DH10B%3A973498..975444,REL606%3A937053..938999,BW2952%3A822538..824484]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=822538&end=824484&gene=macB&aa=mtpllelkdirrsypagdeqvevlkgisldiyagemvaivgasgsgkstlmnilgcldkatsgtyrvagqdvatldadalaqlrrehfgfifqryhllshltaeqnvevpavyaglerkqrllraqellqrlgledrteyypaqlsggqqqrvsiaralmnggqviladeptgaldshsgeevmailhqlrdrghtviivthdpqvaaqaervieirdgeivrnppaiekvnvtggtepvvntvsgwrqfvsgfnealtmawralaankmrtlltmlgiiigiasvvsivvvgdaakqmvladirsigtntidvypgkdfgdddpqyqqalkyddliaiqkqpwvasatpavsqnlrlrynnvdvaasangvsgdyfnvygmtfsegntfnqeqlngraqvvvldsntrrqlfphkadvvgevilvgnmparvigvaeekqsmfgsskvlrvwlpystmsgrvmgqswlnsitvrvkegfdsaeaeqqltrllslrhgkkdfftwnmdgvlktvekttrtlqlfltlvavislvvggigvmnimlvsvtertreigirmavgarasdvlqqflieavlvclvggalgitlslliaftlqlflpgweigfsplalllaflcstvtgilfgwlparnaarldpvdalare]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=macB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=macB]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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MacABTolC exports 14-15 membered lactone macrolides, e.g. erythromycin. MacA stimulates MacB ATPase activity (Tikhonova, 2007).<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

macB

Gene Synonym(s)

ECK0870, b0879, JW0863, ybjZ[1], ybjZ

Product Desc.

MacB[2][3];

Component of MacAB macrolide efflux transporter complex[2]; MacAB-TolC Macrolide Efflux Transport System[3]

ABC-type macrolide efflux transporter, with MacA and TolC[4]

Product Synonyms(s)

fused macrolide transporter subunits of ABC superfamily: ATP-binding component[1], membrane component[1], YbjZ[2][1], MacB[2][1], B0879[2][1] , ECK0870, JW0863, ybjZ, b0879

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): macB[2], macAB[3]

Regulation/Activity
Quick Links



        

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Notes

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MacABTolC exports 14-15 membered lactone macrolides, e.g. erythromycin. MacA stimulates MacB ATPase activity (Tikhonova, 2007).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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