macB:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

macB

Gene Synonym(s)

ECK0870, b0879, JW0863, ybjZ[1], ybjZ

Product Desc.

MacB[2][3];

Component of MacAB macrolide efflux transporter complex[2]; MacAB-TolC Macrolide Efflux Transport System[3]

ABC-type macrolide efflux transporter, with MacA and TolC[4]

Product Synonyms(s)

fused macrolide transporter subunits of ABC superfamily: ATP-binding component[1], membrane component[1], YbjZ[2][1], MacB[2][1], B0879[2][1] , ECK0870, JW0863, ybjZ, b0879

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): macB[2], macAB[3]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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MacABTolC exports 14-15 membered lactone macrolides, e.g. erythromycin. MacA stimulates MacB ATPase activity (Tikhonova, 2007).[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.