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{{Tab On|Quickview|groS}}{{Tab|Gene|groS}}{{Tab|Gene Product(s)|groS}}{{Tab|Expression|groS}}{{Tab|Evolution|groS}}{{Tab|On One Page|groS}}{{TabsBottom}}
{{Tab On|Quickview|groS}}{{Tab|Gene|groS}}{{Tab|Gene Product(s)|groS}}{{Tab|Expression|groS}}{{Tab|Evolution|groS}}{{Tab|On One Page|groS}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[groS:Gene|''groS]]'' (synonyms: ''ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB, tabA'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''groS''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[groS:Gene_Product(s)|GroS product]]<ref name='LIB:Riley_2006'/>: Cpn10 chaperonin GroES, small subunit of GroESL<ref name='LIB:Riley_2006'/>, GroE<ref name='LIB:EcoCyc10.6'/>, B4142<ref name='LIB:EcoCyc10.6'/>, Hdh<ref name='LIB:EcoCyc10.6'/>, TabA<ref name='LIB:EcoCyc10.6'/>, GroS<ref name='LIB:EcoCyc10.6'/>, GroES<ref name='LIB:EcoCyc10.6'/>, MopB<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:GroEL-GroES Chaperonin-CPLX|GroEL-GroES Chaperonin-CPLX]]<ref name='LIB:EcoCyc11.1'/>
''ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB ''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, TabB''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:GroEL-GroES Chaperonin-CPLX|GroEL-GroES Chaperonin-CPLX]]<ref name='LIB:EcoCyc11.1'/>


Chaperonin Cpn10; GroESL small subunit GroES; phage morphogenesis<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''Cpn10 chaperonin GroES, small subunit of GroESL<ref name='LIB:Riley_2006'/>, GroE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4142<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TabA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroES<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MopB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4136, groES, JW4102, mopB, TabB, b4142''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:groS|groS]]<ref name='LIB:EcoCyc10.6'/>, groS, groES  
transcription unit(s): [[:Category:Txn_unit:groS|groS]]<ref name='LIB:EcoCyc10.6'/>, groS, groES  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=groS&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10600]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000593&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=groS&loc=MG1655%3A4368711..4369004,W3110%3A4375368..4375661,DH10B%3A4469073..4469366,REL606%3A4458139..4458591,REL606%3A4349409..4349702,BW2952%3A4307446..4307739]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4307446&end=4307739&gene=groS&aa=mnirplhdrvivkrkevetksaggivltgsaaakstrgevlavgngrilengevkpldvkvgdivifndgygvksekidneevlimsesdilaivea]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=groS+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=groS]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
GroS binds and regulates rpoH.  Cells deficient in GroES and GroEL lyse due to inability to produce cell walls as a result of the reduced level of DapA, the first enzyme in the DAP synthesis pathway. Growth below 8C is impaired due to GroESL inactivation and can be rescued by transgenic Oleispira antarctica Cpn10/60.  Overproduction of GroESL can supress tig/dnaK synthetic lethality at 30 degrees C. Binds TrxA (Kumar, 2004).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

groS

Gene Synonym(s)

ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB [1][2], TabB

Product Desc.

GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity[2][3];

Component of GroEL-GroES Chaperonin-CPLX[3]

Chaperonin Cpn10; GroESL small subunit GroES; phage morphogenesis[4]

Product Synonyms(s)

Cpn10 chaperonin GroES, small subunit of GroESL[1], GroE[2][1], B4142[2][1], Hdh[2][1], TabA product[2][1], GroS[2][1], GroES[2][1], MopB[2][1] , ECK4136, groES, JW4102, mopB, TabB, b4142

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): groS[2], groS, groES

Regulation/Activity
Quick Links



        

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Notes

[back to top]


GroS binds and regulates rpoH. Cells deficient in GroES and GroEL lyse due to inability to produce cell walls as a result of the reduced level of DapA, the first enzyme in the DAP synthesis pathway. Growth below 8C is impaired due to GroESL inactivation and can be rescued by transgenic Oleispira antarctica Cpn10/60. Overproduction of GroESL can supress tig/dnaK synthetic lethality at 30 degrees C. Binds TrxA (Kumar, 2004).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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