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{{Tab On|Quickview|iclR}}{{Tab|Gene|iclR}}{{Tab|Gene Product(s)|iclR}}{{Tab|Expression|iclR}}{{Tab|Evolution|iclR}}{{Tab|On One Page|iclR}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[iclR:Gene|''iclR]]'' (synonyms: ''ECK4010, b4018, JW3978'')<ref name='LIB:Riley_2006'/>
''iclR''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[iclR:Gene_Product(s)|IclR product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B4018<ref name='LIB:EcoCyc10.6'/>, IclR<ref name='LIB:EcoCyc10.6'/>, acetate operon repressor<ref name='LIB:EcoCyc10.6'/>
''ECK4010, b4018, JW3978''<ref name='LIB:Riley_2006'/>, JW3978''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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IclR transcriptional repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
IclR transcriptional repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
Repressor of aceBA operon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B4018<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IclR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, acetate operon repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4010, JW3978, b4018''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:iclR|iclR]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:iclR|iclR]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=iclR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10491]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000484&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=iclR&loc=MG1655%3A4221651..4220827,W3110%3A4227218..4226394,REL606%3A4202559..4201735,DH10B%3A4321347..4320523,BW2952%3A4110507..4111331]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4110507&end=4111331&gene=iclR&aa=mkmistiqkketvmvapipakrgrkpavatapatgqvqsltrglkllewiaesngsvaltelaqqaglpnstthrllttmqqqgfvrqvgelghwaigahafmvgssflqsrnllaivhpilrnlmeesgetvnmavldqsdheaiiidqvqcthlmrmsapiggklpmhasgagkaflaqlseeqvtkllhrkglhaythatlvspvhlkedlaqtrkrgysfddeehalglrclaacifdehrepfaaisisgpisritddrvtefgamvikaakevtlayggmr]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=iclR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=iclR]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
Tetrameric IclR binds to the aceBA operator and dimeric IclR is inactive. Glyoxylate dissociates IclR and favors dimers; pyruvate promotes binding and favors tetramers (Lorca, 2007).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

iclR

Gene Synonym(s)

ECK4010, b4018, JW3978[1], JW3978

Product Desc.

IclR transcriptional repressor[2][3]

Repressor of aceBA operon[4]

Product Synonyms(s)

DNA-binding transcriptional repressor[1], B4018[2][1], IclR[2][1], acetate operon repressor[2][1] , ECK4010, JW3978, b4018

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): iclR[2]

Regulation/Activity
Quick Links



        

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Notes

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Tetrameric IclR binds to the aceBA operator and dimeric IclR is inactive. Glyoxylate dissociates IclR and favors dimers; pyruvate promotes binding and favors tetramers (Lorca, 2007).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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