mcrB:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK4336, b4346, JW5871, rglB''<ref name='LIB:Riley_2006'/> | ''ECK4336, b4346, JW5871, rglB''<ref name='LIB:Riley_2006'/>, rglB'' | ||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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5-methylcytosine-specific restriction enzyme McrBC, subunit McrB<ref name='LIB:Riley_2006'/>, B4346<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RglB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, McrB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''5-methylcytosine-specific restriction enzyme McrBC, subunit McrB<ref name='LIB:Riley_2006'/>, B4346<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RglB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, McrB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK4336, JW5871, rglB, b4346'' | ||
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!align=left {{table_heading_style}} |Function from GO | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left {{table_heading_style}} |Quick Links | !align=left {{table_heading_style}} |Quick Links | ||
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[http://porteco.org/AjaxSearch.jsp?searchString=mcrB&s=search | [[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mcrB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10574]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000567&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mcrB&loc=MG1655%3A4577360..4575981,W3110%3A4584017..4582638,REL606%3A4557282..4555903,BW2952%3A4514465..4515844]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4514465&end=4515844&gene=mcrB&aa=mrkaylmesiqpwiekfikqaqqqrsqstkdyptsyrnlrvklsfgygnftsipwfaflgegqeasngiypvilyykdfdelvlaygisdtnephaqwqfssdipktiaeyfqatsgvypkkygqsyyacsqkvsqgidytrfasmldniindyklifnsgksvippmsktesycledalndlfipettietilkrltikkniilqgppgvgktfvarrlaylltgekapqrvnmvqfhqsysyedfiqgyrpngvgfrrkdgifynfcqqakeqpekkyifiideinranlskvfgevmmlmehdkrgenwsvpltysendeerfyvpenvyiiglmntadrslavvdyalrrrfsfidiepgfdtpqfrnfllnkkaepsfveslcqkmnelnqeiskeatilgkgfrighsyfccgledgtspdtqwlneivmtdiaplleeyffddpykqqkwtnkllgds]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mcrB+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mcrB]] | ||
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Latest revision as of 21:48, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
mcrB |
|---|---|
| Gene Synonym(s) |
ECK4336, b4346, JW5871, rglB[1], rglB |
| Product Desc. |
McrB subunit of 5-methylcytosine restriction system[2][3]; Component of McrBC restriction endonuclease[3] McrBC restriction endonuclease, catalytic subunit; 5-methylcytosine-specific; requires GTP, inhibited by ATP[4] |
| Product Synonyms(s) |
5-methylcytosine-specific restriction enzyme McrBC, subunit McrB[1], B4346[2][1], RglB[2][1], McrB[2][1] , ECK4336, JW5871, rglB, b4346 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
McrB-S is an alternative product initiating at codon 162. McrB-S is seen in some overexpression constructs but has not yet been observed as a native protein. McrB-S has no known function.[4]
In vitro, purified McrBs modulates the cleavage activity of McrBC, probably through binding to McrC.[5],
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Panne, D et al. (1998) McrBs, a modulator peptide for McrBC activity. EMBO J. 17 5477-83 PubMed