lptB:Quickview: Difference between revisions

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{{Tab On|Quickview|lptB}}{{Tab|Gene|lptB}}{{Tab|Gene Product(s)|lptB}}{{Tab|Expression|lptB}}{{Tab|Evolution|lptB}}{{Tab|On One Page|lptB}}{{TabsBottom}}
{{Tab On|Quickview|lptB}}{{Tab|Gene|lptB}}{{Tab|Gene Product(s)|lptB}}{{Tab|Expression|lptB}}{{Tab|Evolution|lptB}}{{Tab|On One Page|lptB}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[lptB:Gene|''lptB]]'' (synonyms: ''yhbG, ECK3190, b3201, JW3168'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''lptB''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[lptB:Gene_Product(s)|YhbG product]]<ref name='LIB:Riley_2006'/>: predicted transporter subunit: ATP-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3201<ref name='LIB:EcoCyc10.6'/>, YhbG<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:YhbG/YhbN ABC transporter|YhbG/YhbN ABC transporter]]<ref name='LIB:EcoCyc10.6'/>
''yhbG, ECK3190, b3201, JW3168''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, JW3168''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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LptB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
LptB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:YhbG/YhbN ABC transporter|YhbG/YhbN ABC transporter]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:YhbG/YhbN ABC transporter|LptA/LptB ABC transporter]]<ref name='LIB:EcoCyc11.1'/>


Lipopolysaccharide export ABC transporter ATP-binding protein; LptBFG<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''predicted transporter subunit: ATP-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3201<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhbG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3190, JW3168, yhbG, b3201''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:lptB-rpoN-yhbH-ptsN-yhbJ|lptB-rpoN-yhbH-ptsN-yhbJ]]<ref name='LIB:EcoCyc10.6'/>, yhbG-rpoN-yhbH-ptsN-yhbJ, [[:Category:txn_units:lptA-lptB|lptA-lptB]]<ref name='LIB:EcoCyc11.1'/>  
transcription unit(s): [[:Category:Txn_unit:lptB-rpoN-yhbH-ptsN-yhbJ|lptB-rpoN-yhbH-ptsN-yhbJ]]<ref name='LIB:EcoCyc10.6'/>, yhbG-rpoN-yhbH-ptsN-yhbJ, [[:Category:Txn_unit:lptA-lptB|lptA-lptB]]<ref name='LIB:EcoCyc11.1'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=lptB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11680]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001623&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=lptB&loc=MG1655%3A3341966..3342691,W3110%3A3343799..3344524,REL606%3A3279179..3279904,BW2952%3A3229114..3229839]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3229114&end=3229839&gene=lptB&aa=matltaknlakaykgrrvvedvsltvnsgeivgllgpngagktttfymvvgivprdagniiiddddisllplhararrgigylpqeasifrrlsvydnlmavlqirddlsaeqredranelmeefhiehlrdsmgqslsggerrrveiaralaanpkfilldepfagvdpisvidikriiehlrdsglgvlitdhnvretlavcerayivsqghliahgtpteilqdehvkrvylgedfrl]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lptB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=lptB]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
LptB depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Reported to be essential based on depletion of ara-controlled expression (Sperandeo, 2006), however Baba, 2006, constructed a viable deletion strain. Binds TrxA (Kumar, 2004).  RpoE regulon.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

lptB

Gene Synonym(s)

yhbG, ECK3190, b3201, JW3168[1][2], JW3168

Product Desc.

LptB[2][3];

Component of YhbG/YhbN ABC transporter[2]; LptA/LptB ABC transporter[3]

Lipopolysaccharide export ABC transporter ATP-binding protein; LptBFG[4]

Product Synonyms(s)

predicted transporter subunit: ATP-binding component of ABC superfamily[1], B3201[2][1], YhbG[2][1] , ECK3190, JW3168, yhbG, b3201

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): lptB-rpoN-yhbH-ptsN-yhbJ[2], yhbG-rpoN-yhbH-ptsN-yhbJ, lptA-lptB[3]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


LptB depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Reported to be essential based on depletion of ara-controlled expression (Sperandeo, 2006), however Baba, 2006, constructed a viable deletion strain. Binds TrxA (Kumar, 2004). RpoE regulon.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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