lptA:Quickview: Difference between revisions

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{{Tab On|Quickview|lptA}}{{Tab|Gene|lptA}}{{Tab|Gene Product(s)|lptA}}{{Tab|Expression|lptA}}{{Tab|Evolution|lptA}}{{Tab|On One Page|lptA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[lptA:Gene|''lptA]]'' (synonyms: ''yhbN, ECK3189, b3200, JW3167'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''lptA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[lptA:Gene_Product(s)|YhbN product]]<ref name='LIB:Riley_2006'/>: predicted transporter subunit: periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3200<ref name='LIB:EcoCyc10.6'/>, YhbN<ref name='LIB:EcoCyc10.6'/>, [[:Category:Complex:YhbG/YhbN ABC transporter|YhbG/YhbN ABC transporter]]<ref name='LIB:EcoCyc10.6'/>
''yhbN, ECK3189, b3200, JW3167''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>, JW3167''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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LptA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
LptA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:YhbG/YhbN ABC transporter|YhbG/YhbN ABC transporter]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:YhbG/YhbN ABC transporter|LptA/LptB ABC transporter]]<ref name='LIB:EcoCyc11.1'/>


Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''predicted transporter subunit: periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3200<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhbN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3189, JW3167, yhbN, b3200''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s):   
transcription unit(s):   
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=lptA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G7665]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120004213&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=lptA&loc=MG1655%3A3341402..3341959,W3110%3A3343235..3343792,REL606%3A3278615..3279172,BW2952%3A3228550..3229107]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3228550&end=3229107&gene=lptA&aa=mkfktnklslnlvlassllaasipafavtgdtdqpihiesdqqsldmqgnvvtftgnvivtqgtikinadkvvvtrpggeqgkevidgygkpatfyqmqdngkpveghasqmhyelakdfvvltgnaylqqvdsnikgdkitylvkeqkmqafsdkgkrvttvlvpsqlqdknnkgqtpaqkkgn]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lptA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=lptA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
LptA depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Paralogous to Imp. The first 27 aa are a type I signal peptide. RpoE regulon.<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:48, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

lptA

Gene Synonym(s)

yhbN, ECK3189, b3200, JW3167[1][2], JW3167

Product Desc.

LptA[2][3];

Component of YhbG/YhbN ABC transporter[2]; LptA/LptB ABC transporter[3]

Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly[4]

Product Synonyms(s)

predicted transporter subunit: periplasmic-binding component of ABC superfamily[1], B3200[2][1], YhbN[2][1] , ECK3189, JW3167, yhbN, b3200

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links



        

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Notes

[back to top]


LptA depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Paralogous to Imp. The first 27 aa are a type I signal peptide. RpoE regulon.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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