glmS:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''glmS''  
''glmS''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3722, b3729, JW3707''<ref name='LIB:Riley_2006'/>
''ECK3722, b3729, JW3707''<ref name='LIB:Riley_2006'/>, JW3707''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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L-glutamine:D-fructose-6-phosphate aminotransferase<ref name='LIB:Riley_2006'/>, B3729<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlmS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''L-glutamine:D-fructose-6-phosphate aminotransferase<ref name='LIB:Riley_2006'/>, B3729<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlmS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3722, JW3707, b3729''
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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
<GO_nr />
* GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
'''Biological Process'''
* GO:0006048 UDP-N-acetylglucosamine biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Cellular Component'''
* GO:0005829 cytosol ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Quick Links
!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=glmS&loc=MG1655:3911691..3909862,W3110:3723013..3724842,REL606:3874034..3872205 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3874034&end=3872205&gene=glmS&aa=mcgivgaiaqrdvaeilleglrrleyrgydsaglavvdaeghmtrlrrlgkvqmlaqaaeehplhggtgiahtrwathgepsevnahphvsehivvvhngiienheplreelkargytfvsetdteviahlvnwelkqggtlreavlraipqlrgaygtvimdsrhpdtllaarsgsplviglgmgenfiasdqlallpvtrrfifleegdiaeitrrsvnifdktgaevkrqdiesnlqydagdkgiyrhymqkeiyeqpnaikntltgrishgqvdlselgpnadellskvehiqilacgtsynsgmvsrywfeslagipcdveiasefryrksavrrnslmitlsqsgetadtlaglrlskelgylgslaicnvpgsslvresdlalmtnagteigvastkafttqltvllmlvaklsrlkgldasiehdivhglqalpsrieqmlsqdkriealaedfsdkhhalflgrgdqypialegalklkeisyihaeayaagelkhgplalidadmpvivvapnnelleklksnieevrarggqlyvfadqdagfvssdnmhiiemphveeviapifytvplqllayhvalikgtdvdqprnlaksvtve Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=glmS+AND+escherichia+coli Pubmed(glmS)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=glmS Textpresso(glmS)]
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=glmS&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10382]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000375&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=glmS&loc=MG1655%3A3911691..3909862,W3110%3A3723013..3724842,REL606%3A3874034..3872205,BW2952%3A3798195..3800024]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3798195&end=3800024&gene=glmS&aa=mcgivgaiaqrdvaeilleglrrleyrgydsaglavvdaeghmtrlrrlgkvqmlaqaaeehplhggtgiahtrwathgepsevnahphvsehivvvhngiienheplreelkargytfvsetdteviahlvnwelkqggtlreavlraipqlrgaygtvimdsrhpdtllaarsgsplviglgmgenfiasdqlallpvtrrfifleegdiaeitrrsvnifdktgaevkrqdiesnlqydagdkgiyrhymqkeiyeqpnaikntltgrishgqvdlselgpnadellskvehiqilacgtsynsgmvsrywfeslagipcdveiasefryrksavrrnslmitlsqsgetadtlaglrlskelgylgslaicnvpgsslvresdlalmtnagteigvastkafttqltvllmlvaklsrlkgldasiehdivhglqalpsrieqmlsqdkriealaedfsdkhhalflgrgdqypialegalklkeisyihaeayaagelkhgplalidadmpvivvapnnelleklksnieevrarggqlyvfadqdagfvssdnmhiiemphveeviapifytvplqllayhvalikgtdvdqprnlaksvtve]]&nbsp;&nbsp; [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=glmS+AND+escherichia+coli]]&nbsp;&nbsp; [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=glmS]]&nbsp;&nbsp;


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Latest revision as of 21:50, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

glmS

Gene Synonym(s)

ECK3722, b3729, JW3707[1], JW3707

Product Desc.

GlmS[2][3];

Component of L-glutamine:D-fructose-6-phosphate aminotransferase[2][3]

Glucosamine-6-phosphate synthase; glucosamine--fructose-6-phosphate aminotransferase; C-terminal F6P-binding domain has isomerase activity[4]

Product Synonyms(s)

L-glutamine:D-fructose-6-phosphate aminotransferase[1], B3729[2][1], GlmS[2][1] , ECK3722, JW3707, b3729

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): glmUS[2]

Regulation/Activity
Quick Links



        

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Notes

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GlmS synthesis s negatively feedback regulated by glucosamine-6-phosphate, which probably causes YhbJ to cleave and inactivate the GlmZ sRNA; GlmZ upregulates glmS mRNA post-translationally (Kalamorz, 2007). THe GlmY sRNA also regulates glmS post-transcriptionally (Urban, 2007). GlmS can be inactivated by various halomethyl and methyl ketone derivatives, of which bromomethyl ketone derivative is most effective because of its high binding affinity.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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