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{{Tab On|Quickview|pbpC}}{{Tab|Gene|pbpC}}{{Tab|Gene Product(s)|pbpC}}{{Tab|Expression|pbpC}}{{Tab|Evolution|pbpC}}{{Tab|On One Page|pbpC}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[pbpC:Gene|''pbpC]]'' (synonyms: ''ECK2515, b2519, JW2503, yfgN'')<ref name='LIB:Riley_2006'/>
''pbpC''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[pbpC:Gene_Product(s)|PbpC product]]<ref name='LIB:Riley_2006'/>: fused transglycosylase<ref name='LIB:Riley_2006'/>, transpeptidase<ref name='LIB:Riley_2006'/>, B2519<ref name='LIB:EcoCyc10.6'/>, YfgN<ref name='LIB:EcoCyc10.6'/>, PbpC<ref name='LIB:EcoCyc10.6'/>, PBP1C<ref name='LIB:EcoCyc10.6'/>
''ECK2515, b2519, JW2503, yfgN''<ref name='LIB:Riley_2006'/>, yfgN''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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putative peptidoglycan enzyme<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
putative peptidoglycan enzyme<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
Penicillin-binding protein PBP1C murein transglycosylase<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused transglycosylase<ref name='LIB:Riley_2006'/>, transpeptidase<ref name='LIB:Riley_2006'/>, B2519<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YfgN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PbpC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PBP1C<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2515, JW2503, yfgN, b2519''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:pbpC|pbpC]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:pbpC|pbpC]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=pbpC&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G7322]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120003894&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=pbpC&loc=MG1655%3A2645347..2643035,W3110%3A2645981..2643669,REL606%3A2568144..2565832,DH10B%3A2737112..2734800,BW2952%3A2528840..2531152]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2528840&end=2531152&gene=pbpC&aa=mprlltkrgcwitlaaapfllflaawgadklwplplhevnparvvvaqdgtplwrfadadgiwrypvtiedvsprylealinyedrwfwkhpgvnpfsvaraawqdltsgrvisggstltmqvarlldphpktfggkirqlwralqlewhlskreiltlylnrapfggtlqgigaaswaylgkspanlsyseaamlavlpqapsrlrpdrwperaeaarnkvlermavqgvwsreqvkesreepiwlaprqmpqlaplfsrmmlgksksdkitttldaglqrrleelaqnwkgrlpprsslamivvdhtdmrvrgwvgsvdlnddsrfghvdmvnsirspgsvlkpfvyglaldeglihpasllqdvprrtgdyrpgnfdsgfhgpismsealvrslnlpavqvleaygpkrfaaklrnvglplylpngaapnlslilggagakledmaaaytafarhgkagklrlqpddpllerplmssgaawiirrimadeaqplpdsalprvaplawktgtsygyrdawaigvnaryvigiwtgrpdgtpvvgqfgfasavpllnqvnnillsrsanlpedprpnsvtrgvicwpggqslpegdgncrrrlatwlldgsqpptlllpeqegingirfpiwldengkrvaadcpqarqeminvwplplepwlpaserravrlppastscppyghdaqlplqltgvrdgaiikrlpgaaeatlplqssggagerwwflngepltergrnvtlhltdkgdyqllvmddvgqiatvkfvmq]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=pbpC+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=pbpC]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
PbpC has a penicillin-insensitive transglycosylase N-terminal domain. PbpC has a transpeptidase-like C-terminal domain that does not seem to be functional. PbpC is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:47, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

pbpC

Gene Synonym(s)

ECK2515, b2519, JW2503, yfgN[1], yfgN

Product Desc.

putative peptidoglycan enzyme[2][3]

Penicillin-binding protein PBP1C murein transglycosylase[4]

Product Synonyms(s)

fused transglycosylase[1], transpeptidase[1], B2519[2][1], YfgN[2][1], PbpC[2][1], PBP1C[2][1] , ECK2515, JW2503, yfgN, b2519

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pbpC[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


PbpC has a penicillin-insensitive transglycosylase N-terminal domain. PbpC has a transpeptidase-like C-terminal domain that does not seem to be functional. PbpC is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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