birA:Quickview: Difference between revisions

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{|   id="I49aee142a65d9"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[birA:Gene|''birA]]'' (synonyms: ''ECK3965, b3973, JW3941, bioR, dhbB'')<ref name='LIB:Riley_2006'/>
''birA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[birA:Gene_Product(s)|BirA product]]<ref name='LIB:Riley_2006'/>: bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding product, B3973 product, BioR product, DhbB product, biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor product, biotin ligase product, BirA transcriptional repressor product
''ECK3965, b3973, JW3941, bioR, dhbB''<ref name='LIB:Riley_2006'/>, dhbB''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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BIOTINLIG-MONOMER<ref name='LIB:EcoCyc10.6'/> BirA transcriptional repressor, biotin-[acetyl-CoA-carboxylase] ligase<ref name='LIB:EcoCyc11.1'/>


Bifunctional biotin protein ligase, biotin operon repressor; biotin-[acetyl-CoA carboxylase] holoenzyme synthase; monomeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding<ref name='LIB:Riley_2006'/>, B3973<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BirA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BioR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DhbB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, biotin ligase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BirA transcriptional repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , bioR, dhbB, ECK3965, JW3941, b3973''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:murB|murB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:murB|murB]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=birA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10123]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000119&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=birA&loc=MG1655%3A4171105..4172070,W3110%3A3463599..3462634,REL606%3A4152693..4153658,DH10B%3A4270802..4271767,BW2952%3A4060785..4061750]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4060785&end=4061750&gene=birA&aa=mkdntvplkliallangefhsgeqlgetlgmsraainkhiqtlrdwgvdvftvpgkgyslpepiqllnakqilgqldggsvavlpvidstnqylldrigelksgdaciaeyqqagrgrrgrkwfspfganlylsmfwrleqgpaaaiglslvigivmaevlrklgadkvrvkwpndlylqdrklagilveltgktgdaaqivigaginmamrrveesvvnqgwitlqeaginldrntlaamlirelraalelfeqeglapylsrwekldnfinrpvkliigdkeifgisrgidkqgallleqdgiikpwmggeislrsaek]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=birA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=birA]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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Biotinyl-5'-AMP is the co-repressor and is also synthesized by BirA (Cronan, 1988). BirA biotinylates AccB on K122. The biotin operon is regulated by the rate of protein biotination (Cronan, 1989).<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

birA

Gene Synonym(s)

ECK3965, b3973, JW3941, bioR, dhbB[1], dhbB

Product Desc.

Bifunctional biotin protein ligase, biotin operon repressor; biotin-[acetyl-CoA carboxylase] holoenzyme synthase; monomeric[2]

Product Synonyms(s)

bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding[1], B3973[3][1], BirA[3][1], BioR[3][1], DhbB[3][1], biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor[3][1], biotin ligase[3][1], BirA transcriptional repressor[3][1] , bioR, dhbB, ECK3965, JW3941, b3973

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): murB[3]

Regulation/Activity
Quick Links



        

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Notes

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Biotinyl-5'-AMP is the co-repressor and is also synthesized by BirA (Cronan, 1988). BirA biotinylates AccB on K122. The biotin operon is regulated by the rate of protein biotination (Cronan, 1989).[2]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
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