cysQ:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[cysQ:Gene|''cysQ]]'' (synonyms: ''ECK4210, b4214, JW4172, amt, amtA'')<ref name='LIB:Riley_2006'/>
''cysQ''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[cysQ:Gene_Product(s)|CysQ product]]<ref name='LIB:Riley_2006'/>: PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase product, B4214 product, Amt product, AmtA product
''ECK4210, b4214, JW4172, amt, amtA''<ref name='LIB:Riley_2006'/>, amtA''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


3'-phosphoadenosine 5'-phosphate (pAp) phosphatase; converts pAp to AMP; inhibited by lithium and calcium, leading to pAP accumulation; probable PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase: probably converts PAPS to<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase<ref name='LIB:Riley_2006'/>, B4214<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Amt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AmtA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysQ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , amt, amtA, ECK4210, JW4172, b4214''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:cysQ|cysQ]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:cysQ|cysQ]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=cysQ&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10043]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000039&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=cysQ&loc=MG1655%3A4434778..4435518,W3110%3A4441435..4442175,REL606%3A4421749..4422489,BW2952%3A4373513..4374253]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4373513&end=4374253&gene=cysQ&aa=mldqvcqlarnagdaimqvydgtkpmdvvskadnspvtaadiaahtvimdglrtltpdvpvlseedppgwevrqhwqrywlvdpldgtkefikrngeftvnialidhgkpilgvvyapvmnvmysaaegkawkeecgvrkqiqvrdarpplvvisrshadaelkeylqqlgehqttsigsslkfclvaegqaqlyprfgptniwdtaaghavaaaagahvhdwqgkpldytpresflnpgfrvsiy]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cysQ+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=cysQ]]&nbsp;&nbsp;


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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

cysQ

Gene Synonym(s)

ECK4210, b4214, JW4172, amt, amtA[1], amtA

Product Desc.

affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis[2][3]

3'-phosphoadenosine 5'-phosphate (pAp) phosphatase; converts pAp to AMP; inhibited by lithium and calcium, leading to pAP accumulation; probable PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase: probably converts PAPS to[4]

Product Synonyms(s)

PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase[1], B4214[2][1], Amt[2][1], AmtA[2][1], CysQ[2][1] , amt, amtA, ECK4210, JW4172, b4214

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): cysQ[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]


CysQ is a main target of lithium toxicity in vivo. CysQ (AmtA) was originally thought to be involved in ammonium transport. CysQ may be part of a futile sulfur cycle with APS kinase CysC.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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