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{| | {| id="C49aee59f99e87" class=" tableEdit New_Quickview_Table" | ||
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''fis'' | ''fis'' | ||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/> | ''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/>, nbp'' | ||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3248, JW3229, nbp, b3261'' | ||
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!align=left {{table_heading_style}} |Function from GO | |||
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<GO_nr /> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=fis&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10317]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000311&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=fis&loc=MG1655%3A3409293..3409589,W3110%3A3411126..3411422,DH10B%3A3507038..3507334,REL606%3A3339162..3339458,BW2952%3A3296441..3296737]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3296441&end=3296737&gene=fis&aa=mfeqrvnsdvltvstvnsqdqvtqkplrdsvkqalknyfaqlngqdvndlyelvlaeveqplldmvmqytrgnqtraalmmginrgtlrkklkkygmn]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=fis+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=fis]] | |||
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Latest revision as of 21:50, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
fis |
|---|---|
| Gene Synonym(s) |
ECK3248, b3261, JW3229, nbp[1], nbp |
| Product Desc. |
Fis transcriptional dual regulator[2][3] Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric[4] |
| Product Synonyms(s) |
global DNA-binding transcriptional dual regulator[1], B3261[2][1], Nbp[2][1], Fis[2][1], site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription[2][1] , ECK3248, JW3229, nbp, b3261 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
fis transcription is supercoiling-dependent. Overexpression causes filamentous biofilm formation. Decreased levels of Fis inhibit open complex formation, inhibiting oriC unwinding by blocking IHF and DnaA low affinity binding sites. Polyamine modulon. Mutations affect chromosomal supercoliing.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.