gspB:Quickview: Difference between revisions

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{|   id="J49aee828dcb0a" class=" tableEdit New_Quickview_Table"


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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[gspB:Gene|''gspB]]'' (synonyms: ''pioO, ECK3309, b3322, JW3284, pinO'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/>
''gspB''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[gspB:Gene_Product(s)|PioO product]]<ref name='LIB:Riley_2006'/>: part of gsp divergon involved in type II protein secretion product, B3322 product, GspB product, PinO product
''pioO, ECK3309, b3322, JW3284, pinO''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/>, pinO''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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calcium-binding protein required for initiation of chromosome replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
calcium-binding protein required for initiation of chromosome replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Part of H-NS-silenced gsp divergon, type II protein secretion; cloned gsp divergon secretes ChiA, requires gspAB operon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''part of gsp divergon involved in type II protein secretion<ref name='LIB:Riley_2006'/>, B3322<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GspB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PioO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PinO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3309, JW3284, pinO, pioO, b3322''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:pioO|pioO]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:gspA-pioO|gspA-pioO]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:pioO|pioO]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:gspA-pioO|gspA-pioO]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=gspB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11263]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001238&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=gspB&loc=MG1655%3A3451949..3451530,W3110%3A4186489..4186908,REL606%3A3381413..3381832,BW2952%3A3338687..3339106]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3338687&end=3339106&gene=gspB&aa=mfefyiaareqketghpgifsrqkhstiiyvicllliclwfagmvlvggyarqlwvlwivkaevtveaetpafkqstqhyffkkqplpvvesveeeddpgvavenapsssedeentveeseekaglrervknalneler]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=gspB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=gspB]]&nbsp;&nbsp;


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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

gspB

Gene Synonym(s)

pioO, ECK3309, b3322, JW3284, pinO[1][2], pinO

Product Desc.

calcium-binding protein required for initiation of chromosome replication[3][2]

Part of H-NS-silenced gsp divergon, type II protein secretion; cloned gsp divergon secretes ChiA, requires gspAB operon[4]

Product Synonyms(s)

part of gsp divergon involved in type II protein secretion[1], B3322[3][1], GspB[3][1], PioO[3][1], PinO[3][1] , ECK3309, JW3284, pinO, pioO, b3322

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pioO[3], gspA-pioO[3]

Regulation/Activity
Quick Links



        

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Notes

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GspB is a distant homolog or convergent analog of exeB of A. hydrophila, which is required for protein export , specifically for the export and assembly of secretin (ExeD/GspD) into the outer membrane. GspB has a single predicted N-terminal transmembrane segment (28-50), followed by a predicted periplasmic domain, which may interact with GspA. GspA may interact with GspB. A divergon is a regulon comprised of two adjacent divergent operons or genes. gspB was initially identified as an ORF that might be the 11.3 kDa PinO protein synthesized in the absence of isoleucine in relA stains (Guzman, 1991). But GspB is predicted to be 15.9 kDa and has isoleucine residues and there is no evidence that gspB encodes the PinO peptide or that it binds calcium. No homology to calmodulin or other calcium-binding proteins is predicted. gspB may have been mistaken for pinO due to use of a downstream ATG as start codon, but the 11 kD C-terminal fragment does have an Ile reside in it, making gspB inconsistent with pinO. pioO was the prior gene name assigned to pinO since the gene name pin was already taken.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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