ispG:Quickview: Difference between revisions

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{|   id="U49aeea6f0ef19"  class=" tableEdit New_Quickview_Table" 
 
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[ispG:Gene|''ispG]]'' (synonyms: ''ECK2511, b2515, JW2499, gcpE'')<ref name='LIB:Riley_2006'/>
''ispG''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[ispG:Gene_Product(s)|IspG product]]<ref name='LIB:Riley_2006'/>: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase product, B2515 product, GcpE product
''ECK2511, b2515, JW2499, gcpE''<ref name='LIB:Riley_2006'/>, gcpE''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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EG10370-MONOMER<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
EG10370<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase<ref name='LIB:Riley_2006'/>, B2515<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GcpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IspG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2511, gcpE, JW2499, b2515''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s):   
transcription unit(s):   
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=ispG&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10370]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000363&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=ispG&loc=MG1655%3A2639826..2638708,W3110%3A2640460..2639342,DH10B%3A2731591..2730473,REL606%3A2562623..2561505,BW2952%3A2524513..2525631]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2524513&end=2525631&gene=ispG&aa=mhnqapiqrrkstriyvgnvpigdgapiavqsmtntrttdveatvnqikalervgadivrvsvptmdaaeafklikqqvnvplvadihfdyrialkvaeygvdclrinpgnigneerirmvvdcardknipirigvnagslekdlqekygeptpqallesamrhvdhldrlnfdqfkvsvkasdvflavesyrllakqidqplhlgiteaggarsgavksaiglglllsegigdtlrvslaadpveeikvgfdilkslrirsrginfiacptcsrqefdvigtvnaleqrlediitpmdvsiigcvvngpgealvstlgvtggnkksglyedgvrkdrldnndmidqlearirakasqldearridvqqvek]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ispG+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=ispG]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
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The IspG substrate is 2C-methyl-d-erythritol 2,4-cyclodiphosphate.  In vitro activity requires auxiliary protein(s), probably as shuttles for redox equivalents.  E. coli ispG(gcpE) complements the P. stuartii aarC1 defect in quorum sensing regulation of gene expression.  The ispG gene is essential.<ref name='LIB:EcoGene'/>




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==References==
==References==
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Latest revision as of 21:49, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

ispG

Gene Synonym(s)

ECK2511, b2515, JW2499, gcpE[1], gcpE

Product Desc.

EG10370[2][3]

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein[4]

Product Synonyms(s)

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase[1], B2515[2][1], GcpE[2][1], IspG[2][1] , ECK2511, gcpE, JW2499, b2515

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


The IspG substrate is 2C-methyl-d-erythritol 2,4-cyclodiphosphate. In vitro activity requires auxiliary protein(s), probably as shuttles for redox equivalents. E. coli ispG(gcpE) complements the P. stuartii aarC1 defect in quorum sensing regulation of gene expression. The ispG gene is essential.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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