mtfA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

mtfA

Gene Synonym(s)

yeeI, ECK1972, b1976, JW1958[1][2], JW1958

Product Desc.

Mlc titration factor[2][3]

DgsA(Mlc) anti-repressor; binds DgsA(Mlc) and blocks its repression of ptsG; cytoplasmic[4]

Product Synonyms(s)

conserved protein[1], B1976[2][1], YeeI[2][1], MtfA[2][1] , ECK1972, JW1958, yeeI, b1976

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yeeI[2]

Regulation/Activity
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Notes

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An mtfA mutation has elevated ptsG activity; overproduction increases pstG and dgsA(mlc) expression. The alternate start codon used here is supported in that the 265 aa protein is sufficient for activity (Becker, 2006) and is likely to be used as the in vivo start codon.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.