uspC:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

uspC

Gene Synonym(s)

yecG, ECK1894, b1895, JW1884[1][2], JW1884

Product Desc.

universal stress protein[2][3]

Stress-induced protein; UV-resistance[4]

Product Synonyms(s)

universal stress protein[1], B1895[2][1], UspC[2][1], YecG[2][1] , ECK1894, JW1884, yecG, b1895

Function from GO

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Knock-Out Phenotype

UspC null mutants lack flagella and are thus completely nonmotile (Nachin et al, 2005; PMID:16159758[5]). UspC null mutants also are sensitive to UV irradiation (Gustavsson et al, 2002; PMID:11849540[6])

Regulation/Expression

transcription unit(s): uspC[2]

Regulation/Activity

Upregulated in response to a variety of stressors in a ppGpp dependent manner (Gustavsson et al, 2002; PMID:11849540[6]).

Quick Links

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Notes

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References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Nachin, L et al. (2005) Differential roles of the universal stress proteins of Escherichia coli in oxidative stress resistance, adhesion, and motility. J. Bacteriol. 187 6265-72 PubMed
  6. ↑ 6.0 6.1 Gustavsson, N et al. (2002) The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage. Mol. Microbiol. 43 107-17 PubMed

[1]

  1. ↑ Gustavsson, N., Diez, A.A., Nystrom, T. 2002. The universal stress protein paralogues of Escherichia coli are co-ordinately regulated and co-operate in the defence against DNA damage. Mol. Microbiol. 43:107-111
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