yafN:Quickview

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Standard Name

yafN

Gene Synonym(s)

ECK0233, b0232, JW0222[1], JW0222

Product Desc.

conserved hypothetical protein with a possible role in spontaneous mutagenesis[2][3]

RelB antitoxin homolog, function unknown; no adjacent RelE-like cognate toxin gene; yafO may be a toxin affected by yafN.[4]

Product Synonyms(s)

predicted antitoxin of the YafO-YafN toxin-antitoxin system[1], B0232[2][1], YafN[2][1] , ECK0233, JW0222, b0232

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yafN[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Notes

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YafN is an StbD homolog and a distant homolog of DnaT. Cognate toxin may have been deleted. LexA regulon. dinB-yafNOP operon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects. LexA regulon.[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.