wzc:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
wzc |
|---|---|
| Gene Synonym(s) |
ECK2054, b2060, JW2045[1], JW2045 |
| Product Desc. |
tyrosine kinase involved in colanic acid biosynthesis[2][3]; Component of capsular polysaccharide export apparatus[3] Autophosphorylating protein tyrosine kinase Wzc, a regulator of capsule production; mutants do not make capsules; cognate with Wzb phosphatase; phosphorylates Ugd[4] |
| Product Synonyms(s) |
protein-tyrosine kinase[1], B2060[2][1], Wzc[2][1] , ECK2054, JW2045, b2060 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): wza-wzb-wzc-wcaAB[2], OP00290, cps, cpsB, cpsGB |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Wzc, but not Wzc-P, activates colanic acid synthesis, needed for capsule production. Wzc-P is dephosphorylated in vivo and in vitro by the Wzb phosphatase. Wzc-P is also dephosphorylated in vitro by the cryptic Etp phosphatase. Wzc has ATPAse activity (Soulat, 2007).[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
