thiG:Quickview

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Standard Name

thiG

Gene Synonym(s)

ECK3982, b3991, JW5549, thiA, thiB[1], thiB

Product Desc.

THIG[2][3];

Component of thiamin biosynthesis ThiGH complex[3]

Thiazole synthase; thiamin-thiazole moiety synthesis; complexes with ThiH[4]

Product Synonyms(s)

thiamin biosynthesis ThiGH complex subunit[1], B3991[2][1], ThiB[2][1], ThiG[2][1] , ECK3982, JW5549, thiB, b3991

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): thiCEFSGH[2]

Regulation/Activity
Quick Links

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Notes

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ThiG synthesizes the thiazole phosphate intermediate (4-methyl-5-beta-hydroxyethyl thiazole phosphate) in thiamine biosynthesis utilizing dehyrodglycine (derived from tyrosine by ThiH in the ThiGH complex), DXP (1-deoxyxylulose 5-phosphate), S-adenosylmethionine (SAM/AdoMet) and the sulfur donor ThiFS thiocarboxylate Kriek, 2007). Aldolase family.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.