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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions


Standard Name


Gene Synonym(s)

ECK2574, b2576, JW2560, rbaB, rhlA[1], rhlA

Product Desc.

SrmB, DEAD-box RNA helicase[2][3]

Putative ATP-dependent RNA helicase; suppresses 50S ribosome assembly defect of rplX(ts); required for effiicient ribosomal 50S subunit assembly; stabilizes exposed mRNA, possibly by protecting or destabilizing secondary structure of RNase E sites[4]

Product Synonyms(s)

ATP-dependent RNA helicase[1], B2576[2][1], RhlA[2][1], RbaB[2][1], SrmB[2][1] , ECK2574, JW2560, rbaB, rhlA, b2576

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): srmB[2]

Quick Links

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SrmB binds RNaseE. Deletion mutant has slow growth phenotype at low temperature.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.