relE:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
relE |
|---|---|
| Gene Synonym(s) |
ECK1557, b1563, JW1555[1], JW1555 |
| Product Desc. |
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system[2][3] Sequence-specific mRNA endoribonuclease, Qin prophage; toxin-antitoxin (TA) pair RelEB, RelE inhibitor of translation cleaves mRNA in A site; binds to its antitoxin RelB and to ribosomes; co-repressor of relB operon transcription; stress-induced[4] |
| Product Synonyms(s) |
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system[1], B1563[2][1], RelE[2][1] , ECK1557, JW1555, b1563 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): relE[2], relBE-hokD[3] |
| Regulation/Activity | |
| Quick Links |
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Notes
Overproduction of RelE has been shown to increase persistance. Overexpression causes filamentous biofilm formation. Overexpression also reported to inhibit growth (Brown, 2003). Degraded by Lon protease.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
