queF:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
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Standard Name |
queF |
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Gene Synonym(s) | |
Product Desc. |
NADPH-dependent nitrile oxidoreductase[2][3]; Component of 7-cyano-7-deazaguanine reductase[3] 7-cyano-7-deazaguanine reductase (NADPH-dependent); converts preQ0 to preQ1, queuosine biosynthesis[4] |
Product Synonyms(s) |
conserved protein[1], B2794[2][1], YqcD[2][1], QueF[2][1] , ECK2789, JW2765, yqcD, b2794 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
Asn, Asp, Tyr, and His tRNA GUN anticodons are modified by queuosine at the G. The product of the QueF reaction is 7-aminomethyl-7-deazaguanine (preQ1). Activity demonstrated in vitro. tgt mutants lack queuosine and are have reduced survival in stationary phase. (Noguchi, 1982).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.