panD:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
panD |
|---|---|
| Gene Synonym(s) |
ECK0130, b0131, JW0127[1], JW0127 |
| Product Desc. |
PanD α & β cleavage products[2][3]; Component of aspartate 1-decarboxylase[3] Aspartate 1-decarboxylase; pantothenate biosynthesis; residues 1-24 cleaved, constitute the beta chain; C-terminal (102aa) constitutes alpha chain[4] |
| Product Synonyms(s) |
aspartate 1-decarboxylase[1], B0131[2][1] , ECK0130, JW0127, b0131 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Mutants have altered acyl-CoA pools. N-terminus of alpha subunit (Ser25) is modified to pyruvic acid and involved in catalysis. Replacing normally modified Ser25 with an alanine inactivates PanD. Sequencing citation: Merkel,W.K. and Nichols,B.P., Nucleotide sequence of the Escherichia coli panBCD gene cluster, unpublished (1993) as cited in GenBank accession number L17086. Aspartate decarboxylase activity was confirmed in K-12 when it was first shown to be PanD (Cronan, 1980).[4]
References
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
