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References Suggestions


Standard Name


Gene Synonym(s)

ECK1866, b1865, JW1854, ntpA, yebD[1], orf17, yebD

Product Desc.

dATP pyrophosphohydrolase[2][3]

Dihydroneopterin triphosphate pyrophosphohydrolase; early step in folate synthesis [4]

Product Synonyms(s)

dATP pyrophosphohydrolase[1], B1865[2][1], YebD[2][1], NudB[2][1], NtpA[2][1] , ECK1866, JW1854, ntpA, orf17, yebD, b1865

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): nudB-yebC-ruvC[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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A nudB mutant has reduced folate synthesis (Gabelli, 2007). Nudix hydrolase. NudB also hydrolyzes dATP, 8-hydroxy-2'-deoxyadenosine 5'-triphosphate and 8-hydroxy-2'-deoxyadenosine 5'-diphosphate.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.