msbA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
msbA |
|---|---|
| Gene Synonym(s) |
ECK0905, b0914, JW0897[1], JW0897 |
| Product Desc. |
ATP-binding transport protein[2][3] Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4] |
| Product Synonyms(s) |
fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1], ECK0905, JW0897, b0914 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
MsbA PDB structures 1JSQ, 1PF4 and 1Z2R, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Chang, 2006). A yhjD point mutation (R134C) allows the deletion of the otherwise essential msbA gene (Mamat, 2007). MsbA point mutations confering S18P or S50P suppress the lethal phenotype of a KDO null gutQ kdsD double mutant (Mamat, 2007).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
