mraY:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
mraY |
|---|---|
| Gene Synonym(s) |
ECK0088, b0087, JW0085, murX[1], murX |
| Product Desc. |
UDP-N-acetylmuramoyl-pentapeptide:undecaprenyl-PO4 phosphatase[2] |
| Product Synonyms(s) |
phospho-N-acetylmuramoyl-pentapeptide transferase[1], B0087[3][1], MurX[3][1], MraY[3][1] , ECK0088, JW0085, murX, b0087 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): mraZW-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ[3] |
| Regulation/Activity | |
| Quick Links |
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Notes
The aspartic acid residues DD115, D116, and D267 are necessary for catalysis. The model suggested indicates that D115 and D116 chelate the Mg2+ cofactor, which in turn binds the pyrophosphate bridge of the UDP-MurNAc-pentapeptide, and D267 acts as the catalytic nucleophile.[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7