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References Suggestions


Standard Name


Gene Synonym(s)

ECK2202, b2210, JW2198, yojH[1], yojH

Product Desc.


Malate oxidoreductase; possibly previously described FAD-dependent phospholipid-activated malate oxidase[4]

Product Synonyms(s)

malate dehydrogenase, FAD/NAD(P)-binding domain[1], B2210[2][1], YojH[2][1], Mqo[2][1] , ECK2202, JW2198, yojH, b2210

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mqo[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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MQO activity is regulated by ArcA-ArcB regulatory system, carbon catabolite and growth phase (expressed in exponential phase with rapid degredation in stationary phase). Growth on pyruvate and acetate media resulted in high MQO activity while glucose media resulted in low activity, however, elevated MQO activity on glucose media in delta-arcA cells has been reported. Over expression of mqo results in depressed growth rates; deletion of mqo is reported to have no phenotype. Binds TrxA (Kumar, 2004).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.