melR:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
melR |
|---|---|
| Gene Synonym(s) |
ECK4111, b4118, JW4079[1], JW4079 |
| Product Desc. |
MelR transcriptional dual regulator[2][3] Transcriptional activator for melAB, AraC family; autoregulatory repressor in absence of co-activator melibiose[4] |
| Product Synonyms(s) |
DNA-binding transcriptional dual regulator[1], B4118[2][1], MelR[2][1], regulator of melibiose operon[2][1] , ECK4111, JW4079, b4118 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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Notes
The C-terminal domain of the RNA polymerase alpha subunit is important for MelR-dependent activation of the melAB promoter. An 18 base pair MelR binding site is necessary for MelR transcription activation because it ensures correct interactions with RNA polymerase sigma subunit.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
