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References Suggestions


Standard Name


Gene Synonym(s)

ECK2071, b2075, JW2060, yegN[1], yegN

Product Desc.


Component of MdtABC RND-type Drug Exporter[2]; MdtABC-TolC Multidrug Efflux Transport System[3]

MdtABC-TolC efflux pump, multidrug resistance; heterodimeric RND-type transporter[4]

Product Synonyms(s)

multidrug efflux system, subunit B[1], B2075[2][1], MdtB[2][1], YegN[2][1] , ECK2071, JW2060, yegN, b2075

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mdtABCD-baeSR[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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mdtABC overexpression confers resistance to deoxycholate and novobiocin. An mdtABC mutant is not sensitive to deoxycholate and Nov. BaeSR, EvgAS regulons.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.