macB:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
macB |
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Gene Synonym(s) |
ECK0870, b0879, JW0863, ybjZ[1], ybjZ |
Product Desc. |
Component of MacAB macrolide efflux transporter complex[2]; MacAB-TolC Macrolide Efflux Transport System[3] ABC-type macrolide efflux transporter, with MacA and TolC[4] |
Product Synonyms(s) |
fused macrolide transporter subunits of ABC superfamily: ATP-binding component[1], membrane component[1], YbjZ[2][1], MacB[2][1], B0879[2][1] , ECK0870, JW0863, ybjZ, b0879 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
MacABTolC exports 14-15 membered lactone macrolides, e.g. erythromycin. MacA stimulates MacB ATPase activity (Tikhonova, 2007).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.