lrp:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

lrp

Gene Synonym(s)

ECK0880, b0889, JW0872, ihb, livR, lrs, lss, lstR, mbf, oppI, rblA, g[1][2], alsB

Product Desc.

Lrp transcriptional dual regulator[2][3]

Global regulatory protein, Leu responsive; regulator of high-affinity branched-chain amino acid transport system; octameric or hexadecameric functional state[4]

Product Synonyms(s)

DNA-binding transcriptional dual regulator, leucine-binding[1], B0889[2][1], LstR[2][1], Mbf[2][1], OppI[2][1], RblA[2][1], Lss[2][1], Lrs[2][1], Ihb[2][1], Lrp[2][1], LivR[2][1], regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system.[2][1] , alsB, ECK0880, ihb, JW0872, livR, lrs, lss, lstR, mbf, oppI, rblA, b0889

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): lrp[2], OP00251

Regulation/Activity
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Notes

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Feast/famine regulatory protein. Homodimers bind adjacent DNA binding sites to form functional octameric state. Lrp wraps DNA and probably plays a role in chromatin organization.[4]



References

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  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.