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References Suggestions


Standard Name


Gene Synonym(s)

ECK1673, b1677, JW1667, mlpA, mulI[1], mulI

Product Desc.

murein lipoprotein[2][3]

Murein lipoprotein; Braun's lipoprotein[4]

Product Synonyms(s)

murein lipoprotein[1], B1677[2][1], MlpA[2][1], Lpp[2][1] , ECK1673, JW1667, mlpA, mulI, b1677

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): lpp[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Lpp binds peptidoglycan, one third has a covalent bond to murein. Lpp is required for cell membrane integrity. Pal restores the outer membrane integrity of an lpp mutant, but overproduced Lpp has no effect on a pal mutant phenotype. First 20 aa are a type II signal peptide. The N-terminus of the unprocessed precursor was sequenced. The lipid attachment to C21 was confirmed.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.