hypA:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
hypA |
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Gene Synonym(s) |
ECK2721, b2726, JW2696[1], JW2696 |
Product Desc. |
accessory protein for nickel incorporation into hydrogenase 3[2][3]; Component of HypA-HypB heterodimer[3] Hydrogenase 3 accessory protein required for activity[4] |
Product Synonyms(s) |
protein involved in nickel insertion into hydrogenases 3[1], B2726[2][1], HypA[2][1] , ECK2721, JW2696, b2726 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression |
transcription unit(s): hypABCDE-fhlA[2], hypABCDE[2], OP00209, hydBEF |
Regulation/Activity | |
Quick Links | |
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Notes
hypA mutants have increased Hydrogenase 2 activity but similar amounts of HypA protein. hypA defect suppressed by expression of hypB-E under foreign promoter, indicating a regulatory or partially redundant function. Paralogous to hybF.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.