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References Suggestions


Standard Name


Gene Synonym(s)

ECK2549, b2552, JW2536, fsrB, hmpA, G679[1][2]

Product Desc.


Flavohemoglobin; nitric oxide dioxygenase; dihydropteridine reductase; GSNO and nitrite reductase; has alkylhydroperoxide reductase activity, possibly involved in the repair of lipid membrane oxidative damage[4]

Product Synonyms(s)

fused nitric oxide dioxygenase[1], dihydropteridine reductase 2[1], B2552[2][1], Hmp[2][1], FsrB[2][1], HmpA[2][1] , ECK2549, fsrB, hmpA, JW2536, b2552

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): hmp[2]

Quick Links

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Upregulated by GSNO in defined medium (aerobic) as part of the NsrR regulon. hmp mutants are defective in macrophage survival and swarming motility (Stevanin, 2007).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.