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References Suggestions


Standard Name


Gene Synonym(s)

ECK1056, b1071, JW1058[1], JW1058, mviS

Product Desc.

anti-sigma factor for FliA (sigma 28)[2][3]

Anti-sigma 28 (FliA) factor; regulator of FlhD[4]

Product Synonyms(s)

anti-sigma factor for FliA (sigma 28)[1], B1071[2][1], FlgM[2][1] , ECK1056, JW1058, mviS, b1071

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): flgMN[2], flgAMN[2]

Quick Links

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Flk prevents premature FlgM secretion. FlgM function is stopped when it is secreted into the periplasm or the medum. FlgM is characterized primarily in Salmonella; the fMet of Salmonella FlgM is clipped. yceN was identified as one of two ORFs adjacent to the flg locus in a region originally named mviS, then renamed mviN and mviM when sequenced; mviMN was thought to be required for mouse virulence in Salmonella, but the mviMN deletion in ST39 also removed flgM (Carsiotis, 1989). flgM was later shown to be able to complement the mviS phenotype, and thus flgM is the real mouse virulence gene mviS in this region of the Salmonella chromosome (Schmitt, 1994).[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.