fhuD:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
fhuD |
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Gene Synonym(s) |
ECK0151, b0152, JW0148[1], JW0148 |
Product Desc. |
Component of iron (III) hydroxamate ABC transporter[2][3]; ferrichrome uptake system[3] Iron-ferrichrome periplasmic binding protein; ferrichrome-dependent iron uptake; binds other hydroxamate siderophores; fhuD mutants are albomycin resistant[4] |
Product Synonyms(s) |
iron-hydroxamate transporter subunit[1], periplasmic-binding component of ABC superfamily[1], B0152[2][1], FhuD[2][1] , ECK0151, JW0148, b0152 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
Verified Tat substrate: FhuD has a predicted Tat-only (Class I) 30 aa signal peptide (Tullman-Ercek, 2007). The N-terminal sequence in Rohrback (1995), cited in Swiss-Prot, does not verify this putative SPI cleavage; it is the product of an enterokinase cleavage of a cloning construct. Rohrback (1995) demonstrated proper folding of FhuD in the cytoplasm prior to export, consistent with FhuD needing the Tat pathway, which exports folded proteins.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.