dksA:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
dksA |
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Gene Synonym(s) |
ECK0144, b0145, JW0141, msmA[1], msmA |
Product Desc. |
RNAP-binding transcriptional regulator of rRNA transcription[2][3] RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters[4] |
Product Synonyms(s) |
RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein[1], B0145[2][1], MsmA[2][1], DksA[2][1] , ECK0144, JW0141, msmA, b0145 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression |
transcription unit(s): |
Regulation/Activity | |
Quick Links | |
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Notes
High copy dksA suppresses mukB and TS growth and filamentation of a dnaK mutant. dksA is also a multicopy suppressor of dnaJ, grpE and prc. dksA transcription is alkali-inducible. Mutations affect chromosomal supercoiling. Binds TrxA (Kumar, 2004). HT_Cmplx24_Cyt: DksA+GreA. dksA and ybiI are paralogs.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.