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Standard Name


Gene Synonym(s)

ECK0830, b0840, JW0824, nucR[1], nucR

Product Desc.

DeoR transcriptional repressor[2][3]

Repressor for deo operon, nupG and tsx; binds deoxyribose-5-phosphate inducer[4]

Product Synonyms(s)

DNA-binding transcriptional repressor[1], B0840[2][1], NucR[2][1], DeoR[2][1], transcriptional repressor for deo operon, tsx, nupG[2][1] , ECK0830, JW0824, nucR, b0840

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): deoR[2]

Quick Links

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The deoR gene is found immediately upstream of the operon. DeoR encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A deoR-deficient mutant has a high level of deoxyriboaldolase and pyrimidine nucleoside phosphorylase. [5] In deoR mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)).


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Zeng, X & Saxild, HH (1999) Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis. J. Bacteriol. 181 1719-27 PubMed