degP:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
degP |
|---|---|
| Gene Synonym(s) |
ECK0160, b0161, JW0157, htrA, ptd[1], ptd |
| Product Desc. |
Component of serine protease Do[3] Periplasmic, membrane-associated serine endoprotease; protease Do, required for high-temperature growth and the degradation of damaged proteins[4] |
| Product Synonyms(s) |
serine endoprotease (protease Do), membrane-associated[1], B0161[2][1], Ptd[2][1], protease Do[2][1], HtrA[2][1] , ECK0160, htrA, JW0157, ptd, b0161 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Autocleavage occurs after Cys95(Cys69 of mature form) or Gln108 (Gln82 of mature form). Autocleavage causes hexameric DegP(HtrA) to dissociate into proteolytically active monomers. Targeted to some proteins by CpxP. Sigma E promoter. Mutants have elevated OM vesiculation (McBroom, 2006). DegP(HtrA) has chaperone activity (Skorko-Glonek, 2007).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
