cusC:Quickview

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Standard Name

cusC

Gene Synonym(s)

ECK0564, b0572, JW0561, ylcB, ibeB, agrC[1][2], silC

Product Desc.

outer membrane factor of the CusCFBA copper efflux system[2][3];

Component of Copper Transporting Efflux System[3]

Silver and copper efflux, OM lipoprotein component; outer membrane factor (OMF) of a tripartate efflux pump; confers copper and silver resistance; required for invasion of brain microvascular endothelial cells in strain K1[4]

Product Synonyms(s)

copper/silver efflux system, outer membrane component[1], B0572[2][1], IbeB[2][1], CusC[2][1], YlcB[2][1], AgrC[2][1] , ECK0564, ibeB, JW0561, silC, ylcB, b0572

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): cusCFBA[2], ylcBCD-ybdE

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Notes

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cusC is in the cusCFBA Cu/Ag efflux operon regulated by Cu and Ag. TolC, MdtQ, MdtP and CusC are paralogs. First 17 aa are a type II signal peptide.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.