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References Suggestions


Standard Name


Gene Synonym(s)

ECK1735, b1737, JW1726, celB, hic[1]

Product Desc.


Component of EIIChb[2][3]

PTS Enzyme IIC(Chb) for N,N'-diacetylchitobiose utilization[4]

Product Synonyms(s)

N,N'-diacetylchitobiose-specific enzyme IIC component of PTS[1], B1737[2][1], ChbC[2][1], Hic[2][1], CelB[2][1] , celB, ECK1735, JW1726, b1737

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): chbBCARFG[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The chb operon is induced by N,N'-diacetylchitobiose. The chb operon was previously thought to encode a cryptic cel operon for a cellobiose degradation system. The Cel+ phenotype is due to mutations making expression chitobiose-independent, but a fully induced operon did not support growth on cellobiose, implying a mutation altering the substrate specificity is needed; several candidate mutations were noted in Genbank, but not proven to alter the specificity of the system (Keyhani, 1997). In contrast, a later study claim that mutations making the operon expression high-level constitutive by chbR and nagC mutations are sufficient for the Cel+ phenotype and that no mutations altering substrate specificity are required (Kachroo, 2007).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.