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References Suggestions


Standard Name


Gene Synonym(s)

ECK2189, b2197, JW2185, yejS[1], yejS

Product Desc.


Component of [[:Category:Complex:CcmABCDEFGH cytochrome c biogenesis system|CcmABCDEFGH cytochrome c biogenesis system]][3]

Heme chaperone, membrane-anchored, periplasmic[4]

Product Synonyms(s)

periplasmic heme chaperone[1], B2197[2][1], YejS[2][1], CcmE[2][1] , ECK2189, JW2185, yejS, b2197

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): ccmABCDEFGH[2], napFDAGHBC-ccmABCDEFGH[2], aeg-46.5

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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CcmE makes a transient covalent linkage to heme at His-130 and then transfers heme to apocytochrome C in the presence of CcmFGH. Overexpression causes abnormal biofilm architecture.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.