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References Suggestions


Standard Name


Gene Synonym(s)

ECK4386, b4394, JW5801[1], JW5801

Product Desc.


Inosine/xanthosine triphosphatase; may be involved in detoxifying ITP and XTP; dimeric;[4]

Product Synonyms(s)

thiamin metabolism associated protein [1], B4394 [2][1], YjjX [2][1] , ECK4386, JW5801, b4394

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yjjX[2]

Quick Links

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ITP and XTP are products of oxidative damage and inhibitors of transcription, but the physiological significance and in vivo substrates for the in vitro triphosphatase activity is uncertain. The association of YjjX with Ef-Tu is of unknown physiological significance, since Ef-Tu is an abundant and sticky protein. YjjX is implicated in the detoxification of the thiamine metabolism inhibitors bacimethrin and CF3-HMP.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.