lptB:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

lptB

Gene Synonym(s)

yhbG, ECK3190, b3201, JW3168[1][2], JW3168

Product Desc.

LptB[2][3];

Component of YhbG/YhbN ABC transporter[2]; LptA/LptB ABC transporter[3]

Lipopolysaccharide export ABC transporter ATP-binding protein; LptBFG[4]

Product Synonyms(s)

predicted transporter subunit: ATP-binding component of ABC superfamily[1], B3201[2][1], YhbG[2][1] , ECK3190, JW3168, yhbG, b3201

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): lptB-rpoN-yhbH-ptsN-yhbJ[2], yhbG-rpoN-yhbH-ptsN-yhbJ, lptA-lptB[3]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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LptB depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Reported to be essential based on depletion of ara-controlled expression (Sperandeo, 2006), however Baba, 2006, constructed a viable deletion strain. Binds TrxA (Kumar, 2004). RpoE regulon.[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.