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References Suggestions


Standard Name


Gene Synonym(s)

ECK2613, b2617, JW2598, smqA, bamE , smpA[1][2], smpA

Product Desc.

BamE small membrane protein A[3][4] Component of Outer Membrane Protein Assembly Complex[4]

Stabilizes BamABCD OM biogenesis complex; member of a BamABCDBamE multiprotein complex; probable lipoprotein, Cys conserved[2]

Product Synonyms(s)

small membrane lipoprotein[1], B2617[3][1], SmqA[3][1], BamE[3][1], BamE [2] , ECK2613, JW2598, smpA, smqA, b2617

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): bamE[3]

Quick Links


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A consensus has been reached for renaming the genes that encode components of the outer membrane β-barrel assembly machine, (formerly known as the YaeT complex of E. coli or the Omp85 complex of N. meningitidis). The new designation for this multi-component structure is the Bam complex (for beta-barrel assembly machine).

The Bam complex in E. coli consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA). Letters have been assigned on the basis of molecular weight, from highest to lowest [2].

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smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.[2]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7