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References Suggestions


Standard Name


Gene Synonym(s)

ECK2507, b2511, JW5403, engA, yfgK[1], yfgK

Product Desc.

50S ribosomal subunit stability factor[2][3]

Multicopy suppressor of ftsJ; depleted cells form filaments with defective chromosome segregation; GTPase[4]

Product Synonyms(s)

predicted GTP-binding protein[1], B2511[2][1], Der[2][1], YfgK[2][1], EngA[2][1] , ECK2507, engA, JW5403, yfgK, b2511

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yfgL-der[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Der-depletion alters ribosome stability and/or biogenesis, as evidenced by polysome profiles (Bharat, 2006). Der has two tandem GTP-binding domains. der is an essential gene.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.