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References Suggestions


Standard Name


Gene Synonym(s)

ECK2412, b2417, JW2410, gsr, iex, tgs, treD[1], treD

Product Desc.


PTS Enzyme IIAGlc, phosphocarrier for glucose transport; negative control of rpoS[4]

Product Synonyms(s)

glucose-specific enzyme IIA component of PTS[1], B2417[2][1], TreD[2][1], Tgs[2][1], Iex[2][1], Gsr[2][1], Crr[2][1] , ECK2412, gsr, iex, JW2410, tgs, treD, b2417

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): crr[2], ptsHI-crr[2]

Quick Links

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Phosphorylation of Enzyme IIAGlc is necessary for direct translational control of rpoS. Formerly EIII(glc). Dephosphorylation of Enzyme IIAGlc causes inhibition of uptake of a number of non-PTS carbon sources, a process called inducer exclusion. PTS is the phosphoenolpyruvate:carbohydrate phosphotransferase system for the uptake of carbohydrates that are phosphorylated during transport. Binds TrxA (Kumar, 2004).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.