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References Suggestions


Standard Name


Gene Synonym(s)

ECK0730, b0741, JW0731, excC[1], excC

Product Desc.


Component of Tol-Pal Cell Envelope Complex[2]; The Tol-Pal Cell Envelope Complex[3]; The Colicin A Import System[3]; Colicin S4 Transport System[3]

Lipoprotein associated with peptidoglycan; involved in maintaining cell membrane integrity[4]

Product Synonyms(s)

peptidoglycan-associated outer membrane lipoprotein[1], B0741[2][1], ExcC[2][1], Pal[2][1] , ECK0730, excC, JW0731, b0741

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): tolB-pal-ybgF[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Cell envelope integrity is stabilized by the Tol-Pal system linking inner and outer membranes. First 21 aa are a type II signal peptide. Pal restores the outer membrane integrity of an lpp mutant, but overproduced Lpp has no effect on a pal mutant phenotype. Mutants have elevated OM vesiculation (McBroom, 2006).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.